Samantha M. Powell

   
Teaching
Work Experience
Honors/Awards
Conferences Attended
Publications

Education

University of Oklahoma
PhD. (2014 - Present)

Colorado School of Mines
BS in Chemistry and minor in Bioengineering and Life Sciences (2014)


Teaching  

MCAT Course Instructor (2018) 
University of Oklahoma MCAT 

Teaching Assistant (2014-2015)
University of Oklahoma
General Chemistry I (CHEM 1315) and Chemistry II (CHEM1415)

Instructor, Center for Bright Kids (2014)
Luminary summer program (grades 8-11): Organic Chem, Molecule by Molecule
GLOW summer program (grades 6-8): Mini Med-School for Aspiring Doctors


Work Experience

Mycology Intern at IMMY (Summer 2018)
Norman, OK
Helped in the manufacturing and development of fungal disease diagnostics. Assisted in BSL3 and cell culture lab, helped in developing antigen/antibody purification strategies, and learned the manufacturing process of IMMY's products (Enzyme Immunoassay, Immunodiffusion and Complement Fixation).

NSF Fellow at Ft. Sam Houston Air Force Research Lab (Summer 2017)
PI: Dr. Jeffrey Wigle, San Antonio, TX
Investigated the mechanisms behind low level laser therapy (LLLT) or photobiomodulation. Used fluorescence and absorbance based assays to track pathways following low level laser exposure. This research was supported by the NSF Improving Graduate Student Preparedness for the Chemistry Workforce Fellowship.

Undergraduate Research Experience (2013-2014)
PI: Dr. Stephen Boyes, Colorado School of Mines
Synthesized, tested and characterized RAFT agents and pH sensitive polymers to be attached to Gd nanoparticles for use as contrast agents in MRIs for cancerous tumor detection.

PREP Research Fellow at National Institute of Standards and Technology (NIST) (2012-2014)
Reviewed submitted manuscripts from four major thermodynamic science journals. Data was compared to previous data stored in the NIST database using Guided Data Capture (GDC) and Thermo Data Engine (TDE). Older data from scientific journals was reviewed to reassess previously captured data in order to keep the NIST database up to date. 

Honors/Awards 

Provost's Distinction in Teaching Excellence, OU (2015)

Best gradate student poster presentation award -  3rd Annual Symposium on Structural Biology, OU (2015)

OU Graduate College International Travel Scholarship (2016)

NSF Graduate Research Fellowship Honorable Mention (2016)

2nd place graduate student poster presentation award- 4th Annual Symposium on Structural Biology, OU (2016)

NSF Improving Graduate Student Preparedness for the Chemistry Workforce Fellowship (2016)

Graduate Research Scholarship for Excellence in X-ray Based Structural Biology, OU (2017)

Student E-Poster Presentation Honorable Mention in Physical Sciences, American Association for the Advancement for Science Annual Meeting (2018)

Joshua E. Neimark Memorial Travel Award, American Association for the Advancement for Science (2018)

Conferences Attended 

Powell, S. M.; Wang, B.; Herrera, V.; Yang, K.; Nguyen, N.; Thomas, L. M.; Richter-Addo, G. B., Poster: "Structural Comparison of the Interactions Between Hydroxylamine-based Ligands with Myoglobin and Hemoglobin". 6th Annual Symposium on Structural Biology, Norman, OK (2018).

Powell, S. M.; Wang, B.; Herrera, V.; Yang, K.; Nguyen, N.; Richter-Addo, G. B., Poster: "Structural Comparison of the Interactions Between Hydroxylamine-based Ligands with Myoglobin and Hemoglobin". 63rd Annual Oklahoma Pentasectional Meeting, Tulsa, OK (2018).

Powell, S. M.; Wang, B.; Yang, K.; Herrera, V.; Richter-Addo, G. B., Poster: "Formation of Myoglobin-Nitroso Adducts from Amine and Nitro-Containing Drugs". 255th ACS National Meeting, New Orleans, LA (2018).

Powell, S. M.; Wang, B.; Yang, K.; Herrera, V.; Richter-Addo, G. B., Poster: "Formation of Myoglobin-Nitroso Adducts from Amine and Nitro-Containing Drugs". AAAS Annual Meeting, Austin, TX (2018).

Pope, N. J.; Powell, S. M.; Wigle, J. C., Oral Presentation: “Wavelength dependence of intracellular nitric oxide levels in hTERT-RPE cels in vitro”. SPIE Photonics West BiOS, San Francisco, CA (2018). 

Powell, S.; Wang, B.; Herrera, V.; Ye, G.; Richter-Addo, G. B., Poster: "Formation of Myoglobin-Nitroso Adducts from Nitro-Containing Drugs". 5th Annual Symposium on Structural Biology, Norman, OK (2017). 

Powell, S.; Wang, B.; Ye, G.; Copeland, D.; Richter-Addo, G. B., Poster: "Inhibition of heme protein function by nitrosoarene/alkane coordination". 9th International Conference on Porphyrins and Pthalocyanines, Nanjing, China (2016).

Powell, S.; Wang, B.; Hessami, N.; Najar, F.; Thomas, L. M.; West, A. H.; Karr, E. A.; Richter-Addo, G. B., Poster: "Crystal structures of two FMN-dependent nitroreductases from a hypervirulent strain of C. difficile". 4th Annual Symposium on Structural Biology, Norman, OK (2016).

Powell, S.; Wang, B.; Ye, G; Copeland, D.; Richter-Addo, G. B., Poster: "Inhibition of heme protein function by nitrosoarene/alkane coordination". 3rd Annual Symposium on Structural Biology, Norman, OK (2015).

Powell, S.; Zhu, L.; Boyes, S. G., Oral Presentation: "Design and synthesis of pH-responsive block copolymers for use in cancer diagnostics". 247th ACS National Meeting & Exposition, Dallas, TX (2014).

Zhu, L.; Powell, S.; Boyes, S. G., Poster Presentation: "Synthesis of tertiary amine-based pH-responsive block copolymers for use as "smart" MRI contrast agents". 247th ACS National Meeting & Exposition, Dallas, TX (2014).


Publications

Wang, B.; Shi, Y.; Tejaro, J.; Powell, S. M.; Thomas, L. M.; Gladwin, M. T.; Shiva, S.; Zhang, Y.; Richter-Addo, G. B. (2018) Nitrosyl myoglobins and their nitrite precursors: crystal structural and quantum mechanics of molecular mechanics theoretical investigations of preferred Fe-NO ligand orientations in myoglobin distal pockets, Biochemistry, 57: 4788-4802.

Pope, N. J.; Powell, S. M.; Wigle, J. C. (2018) Wavelength dependence of intracellular nitric oxide levels in hTERT-RPE cells in vitro, Proc. SPIE 10477, Mechanisms of Photobiomodulation Therapy XIII, 10477.

Wang, B.; Powell, S. M.; Guan, Y.; Xu, N.; Thomas, L. M.; Richter-Addo, G. B. (2017) "Nitrosoamphetamine Binding to Myoglobin and Hemoglobin: Crystal Structure of the H64A Myoglobin-Nitrosoamphetamine Adduct." Nitric Oxide: Biol. Chem. 67, 26. DOI: 10.1016/j.niox.2017.04.012

Wang, B.; Powell, S. M.; Hessami, N.; Najar, F. Z.; Thomas, L. M.; Karr, E. A.; West, A. H.; Richter-Addo, G. B. (2016) "Crystal Structures of Two Nitroreductases from Hypervirulent Clostridium difficile and Functionally Related Interactions with the Antibiotic Metronidazole." Nitric Oxide: Biol. Chem. 60; pp 32-29.

Zhu, L., Powell, S. and Boyes, S. G. (2015), Synthesis of tertiary amine-based pH-responsive polymers by RAFT Polymerization. J. Polym. Sci. A Polym. Chem., 53: 1010-1022. DOI: 10.1002/pola.27529

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